Pulmonology, Critical Care and Sleep Medicine Specialty Report 2021
Even before the first patient arrived at our doors, a Mount Sinai research team working with CT scans from patients in China noticed that this disease did not look like a normal pneumonia. And once we did start seeing large numbers of patients, other anomalies were quickly evident, including signs that blood clots played a major role, which led to the use of anticoagulation therapy for patients and opened new lines of research to pursue. A separate study showed unique patterns of vascular and thrombosis-induced injury and suggested a unique role for neutrophils in driving acute tracheobronchitis, ARDS, and thrombosis.