Interventional Radiology (IR) is fast becoming the preferred method to address many health issues. IR at Mount Sinai, under the direction of Robert Lookstein, MD, is nationally recognized as one of the top programs for image-guided procedures. The minimally invasive nature of the procedures has led to a paradigm shift from conventional surgery to interventional techniques as the first choice and the preferred method for the treatment of peripheral vascular disease, many aortic pathologies, and venous diseases. It provides a much less invasive approach for treating a wide range of conditions including uterine fibroids, benign prostate hyperplasia, and many cancers. IR provides numerous benefits to patients compared to open surgical techniques including shorter recovery time, less pain, and reduced risk of complication.