Here at Mount Sinai Health System, where we found ourselves at the center of the nation’s largest outbreak in March and April, we saw a rapid rise in patients presenting with COVID-19-associated acute kidney injury that threatened to overwhelm our dialysis programs. We quickly drew on our expertise in peritoneal dialysis (PD) to create an inpatient acute PD program to relieve the stress on our hemodialysis capabilities. We also created successful protocols to keep patients in our existing outpatient hemodialysis program safe, and we are continuing to study COVID-19-related kidney injury to develop therapeutic targets and risk assessment protocols.