Researchers at Mount Sinai are making significant advances in understanding the role of the microbiome in health and disease. Jeremiah Faith, PhD's work focuses on using microbes as a therapeutic tool, particularly for inflammatory bowel disease (IBD). His lab is developing precise treatments based on bacterial strains identified through metagenomic sequencing, which could replace fecal transplants for conditions like recurrent C. difficile infection.

Gang Fang, PhD's laboratory specializes in high-resolution microbiome analysis, leveraging long-read sequencing to differentiate bacterial strains and uncover their subtle, disease-related genetic variations. This innovative approach helps identify bacteria that could pose a higher risk for disease or provide health benefits.

Jose Clemente, PhD’s research explores how early-life exposure to specific microbes influences immune development and the incidence of allergies. By studying populations with low allergy rates, such as Old Order Mennonites, his team aims to understand how changes in microbiome composition may protect against allergic diseases and other immune-related conditions.